|
KMID : 0545120120220050699
|
|
Journal of Microbiology and Biotechnology
2012 Volume.22 No. 5 p.699 ~ p.707
|
|
|
Identification of Reassortant Pandemic H1N1 Influenza Virus in Korean Pigs
|
|
Han Jae-Yeon
Park Sung-Jun
Kim Hye-Kwon
Rho Se-Mi
Giap Van Nguyen
Song Dae-Sub
Kang Bo-Kyu
Moon Hyung-Jun
Yeom Min-Joo
Park Bong-Kyun
|
|
|
Abstract
|
|
|
|
Since the 2009 pandemic human H1N1 influenza A virus emerged in April 2009, novel reassortant strains have been identified throughout the world. This paper describes the detection and isolation of reassortant strains associated with human pandemic influenza H1N1 and swine influenza H1N2 (SIV) viruses in swine populations in South Korea. Two influenza H1N2 reassortants were detected, and subtyped by PCR. The strains were isolated using Madin- Darby canine kidney (MDCK) cells, and genetically characterized by phylogenetic analysis for genetic diversity. They consisted of human, avian, and swine virus genes that were originated from the 2009 pandemic H1N1 virus and a neuraminidase (NA) gene from H1N2 SIV previously isolated in North America. This identification of reassortment events in swine farms raises concern that reassortant strains may continuously circulate within swine populations, calling for the further study and surveillance of pandemic H1N1 among swine.
|
|
|
KEYWORD
|
|
|
H1N2 influenza A virus, pandemic (H1N1) 2009 influenza A virus, reassortment, South Korea, swine
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|